Dosage Forms

RAPID DISSOLVING TABLETS (RDT)

As the name suggests, Rapid Dissolving Tablets are designed to dissentiegrate quickly on the tongue or under the tongue, thereby reducing the need to swallow a tablet or capsule.

Upon introduction into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water for easy administration of active pharmaceutical ingredients.

RDT’s can be particularly useful for children and the elderly with issues swallowing large capsule/tablets. Conditions such as dysphagia (trouble swallowing), hand tremors, certain mental illnesses and developmental disabilities can often impair certain patients ability to swallow commercially available medicines.

They can also benefit if local absorption in the mouth is required for the medication to work. Certain drugs may be absorbed in buccal cavity, resulting in a faster onset of action and increased bioavailability(2).

At Gold Coast Compounding we are proud to offer compounded rapid-dissolve tablets.

ORAL LIQUIDS

At Gold Coast Compounding, we are able to compound various medications into oral liquid form for patients that have trouble taking capsules or tablets, or in cases where there is no liquid form commercially available. Our pharmacists can work with your health practitioner to prepare a safe, effective medication compounded just for you and your family.

Commonly prepared oral liquids include reflux medication for infants and sleeping medication for children. Our pharmacists work hard to ensure your compounded liquid is formulated to have a pleasant taste, and to avoid any components that may cause allergic or adverse reactions for the individual patient.

TOPICAL/TRANSDERMAL CREAMS, GELS & OINTMENTS

The skin is the human body’s largest organ. It covers the entire body and serves as a line of defense against the external invasion of microorganisms and other environmental stressors such as heat, entry of chemicals and toxins, as well as dehydration.

Transdermal drug delivery via the skin can be beneficial because it avoids the risks associated with intravenous therapy and the often unpredictable effects of the drug on the stomach and liver. In certain instances, our pharmacists can work with your doctor or other health practitioner to prepare a medication in a cream, gel, ointment or other topical form to be absorbed into the skin. We compound many skin preparations on a daily basis. Whether it’s a cosmeceutical skin cream or a transdermal hormone gel, our compounding pharmacists are here to help.

If you have already been prescribed a compounded cream, or just want more information on compounded skin preparations, feel free to speak to one of our compounding pharmacists for more information on how we can help.

TROCHES (LOZENGES)

Troches are compounded lozenges that are designed to dissolve and deliver a medicine within the buccal mucosa (the inner lining of cheeks and lips).

Advantages of using a troche over a capsule or tablet include bypassing some of the effects of the liver and gut on metabolising and eliminating the medication. The buccal cavity is the most easily accessible transmucosal site and can allow medication access to the systemic circulation.

Many different medicines can be delivered via troches, including hormones. Troches can be flavoured and sweetened according the individual patient’s preference.

CAPSULES

Here at Gold Coast Compounding we are able to prepare medications into capsules of different sizes, colours, and types. We also offer vet-flavoured capsules (chicken and beef) to make it easier to give medication to your pets.

OTHER SPECIALISED DOSAGE FORMS

• Rectal suppositories
• Vaginal pessaries/creams
• Sublingual drops
• Topicals sprays
• Ear drops
• Nasal sprays
• lip Balms
• Effervescent powders

 

There are compounded medications available that your doctor may not be aware of. If you are interested in learning more, please call one of our compounding pharmacists on (07) 5676 7280 or e-mail us at: [email protected].

 

REFERENCES:

1. Fu Y1, Yang S, Jeong SH, Kimura S, Park K. Orally fast disintegrating tablets: developments, technologies, taste-masking and clinical studies. Crit Rev Ther Drug Carrier Syst. 2004;21(6):433-76.

2. Orally Disintegrating Tablets: A Review Jaysukh J Hirani, Dhaval A Rathod, Kantilal R Vadalia. Tropical Journal of Pharmaceutical Research, April 2009; 8 (2): 161-172

3. Recent advances in gel technologies for topical and transdermal drug delivery. Khurram Rehman and Mohd Hanif Zulfakar. Drug Development And Industrial Pharmacy Vol. 40 , Iss. 4,2014

4. Modeling the oral cavity: In vitro and in vivo evaluations of buccal drug delivery systems. Viralkumar F. Patela, , , Fang Liua, Marc B. Browna, b  Journal of Controlled Release Volume 161, Issue 3, 10 August 2012, Pages 746–756

5. Buccal Drug Delivery: Past, Present and Future – A Review Puratchikody, A; VV, Prasanth; Mathew, Sam T; B, Ashok Kumar. International Journal of Drug Delivery; Bhopal3.2 (2011): 171.

6. G. Wren, R. O. Day, A. J. McLachlan & K. M. Williams (2003) Pharmacokinetics of estradiol, progesterone, testosterone and dehydroepiandrosterone after transbuccal administration to postmenopausal women, Climacteric, 6:2, 104-11