S-adenosylmethionine (SAMe) 400mg, 100 Capsules

$120.00

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S-Adenosylmethionine (SAMe) is a naturally occurring compound found in the body that plays a pivotal role in various biological functions, including mood regulation, liver detoxification, and joint health. As a powerful methyl donor, SAMe helps support over 40 biochemical processes, from neurotransmitter synthesis to the maintenance of healthy cartilage. This supplement offers a potent 400mg dose of SAMe per capsule, designed for those who need higher levels of support for emotional well-being, liver health, or joint function. SAMe is known for its superior bioavailability, meaning that it is efficiently absorbed and utilised by the body for optimal results.

Description

S-adenosylmethionine (SAMe) is essential for nearly all methylation reactions. It is the predominant methyl group donor in the methylation cycle. Methylation and histamine have a direct relationship, where histamine is deactivated by methyl compounds from SAMe. With high histamine levels, the body may become depleted in the methyl groups causing undermethylation.  Low SAMe is generally seen in these patients, due to the lack of methyl groups to deactivate the high histamine levels. Additionally, through SAMe’s action as a methyl donor, its action increases the activity of pathways which increases serotonin and dopamine levels, thereby assisting with mood elevation.

Gold Coast Compounding Nutrients are Practitioner Only Products. Please consult with your Doctor or Compounding Pharmacist to see whether this product is right for you.

Key Benefits

  • Supports Mood and Emotional Well-Being: SAMe is widely recognised for its ability to support mood regulation and promote a positive outlook. It is commonly used to help manage mild to moderate depression and stress, working by increasing the levels of important neurotransmitters like serotonin, dopamine, and norepinephrine.
  • Promotes Joint Health: SAMe is beneficial for individuals experiencing joint discomfort, particularly in conditions like osteoarthritis. It helps reduce inflammation and supports the regeneration of cartilage, leading to improved mobility and reduced pain.
  • Enhances Liver Function: SAMe supports liver detoxification and enhances the production of glutathione, a potent antioxidant that protects the liver from oxidative stress and helps with liver regeneration.
  • Supports Cognitive Health: As a vital compound in neurotransmitter production, SAMe plays an essential role in cognitive function and memory. It may help protect against age-related cognitive decline and improve mental clarity.
  • High Bioavailability: The formulation of SAMe in this supplement ensures excellent absorption, making it a highly effective option for those seeking comprehensive support for their health and well-being.

How to Use

Take 1 capsule daily with food or as directed by your healthcare provider. If higher doses are recommended for specific health concerns (such as mood support or joint health), consult your healthcare professional for personalised dosage guidance.

Safety Information/Precaution

  • Consult your healthcare provider before starting SAMe, particularly if you are pregnant, breastfeeding, or taking medications such as antidepressants (e.g., SSRIs, MAOIs) or other medications affecting serotonin levels.
  • Do not exceed the recommended dosage unless advised by a healthcare provider.
  • Keep out of reach of children.
  • Store in a cool, dry place, away from direct sunlight.
  • Some individuals may experience mild gastrointestinal upset, especially at higher doses. If discomfort occurs, reduce the dosage or consult your doctor.

FAQs

What is SAMe and what does it do?

S-Adenosylmethionine (SAMe) is a naturally occurring compound that plays a crucial role in supporting mood regulation, joint health, liver function, and cognitive performance. It acts as a methyl donor in over 40 biochemical reactions, including the production of important neurotransmitters like serotonin, dopamine, and norepinephrine.

Why should I choose SAMe 400mg over the 200mg version?

SAMe 400mg provides a higher dose of the active ingredient, making it suitable for individuals who need more potent support for mood, joint health, or liver function. The higher dosage may be recommended for those with more severe conditions or who require faster results.

How long does it take for SAMe to work?

The effects of SAMe may vary depending on the individual. For mood support, some people may notice improvements within 1-2 weeks, while joint health or liver function may take several weeks of consistent use to show noticeable benefits.

Can SAMe be taken with other medications?

SAMe can interact with certain medications, particularly antidepressants or other drugs that affect serotonin levels. It’s important to consult with your healthcare provider before using SAMe, especially if you are already taking other medications for mood disorders or cognitive support.

Is SAMe safe for long-term use?

SAMe is generally safe for long-term use when taken at the recommended dosage. However, it’s always best to consult your healthcare provider for personalised advice based on your health needs.

Is this product suitable for vegetarians or vegans?

Please check the product label to confirm whether it meets vegan or vegetarian standards. Typically, SAMe supplements are made with non-animal-derived ingredients, but it’s always a good idea to confirm.

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